LAT2 Protein (AA 27-243) (His tag)

Produktnummer ABIN666998

Produktdetails

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-243

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LAT2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: NTAL, 27-243aa, Human, His tag, E.coli

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol

Lagerung: 4 °C

Antigendetails

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Andere Bezeichnung: NTAL (LAT2 Produkte)

Synonyme: LAB Protein, NTAL Protein, WBSCR15 Protein, WBSCR5 Protein, WSCR5 Protein, LAT2 Protein, MGC139435 Protein, Ntal Protein, Wbscr5 Protein, AW125574 Protein, Wbscr15 Protein, linker for activation of T-cells family member 2 Protein, linker for activation of T cells family, member 2 Protein, LAT2 Protein, Lat2 Protein

Hintergrund: NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS). Recombinant human NTAL, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: LAT2, HSPC046, LAB, WBSCR15, WBSCR5, WSCR5, Non-T-cell activation linker LAB, Lat2, Linker for activation of B cells, Linker for activation of T cells family member 2, Membrane associated adapter molecule, Non T cell activation linker, WBSCR 5, Wbscr15, Williams Beuren syndrome chromosome region 15, Williams Beuren syndrome chromosome region 5. NCBI no.: NP_115853

Molekulargewicht: 26.2 kDa (238aa), confirmed by MALDI-TOF

Pathways: Fc-epsilon Rezeptor Signalübertragung, BCR Signaling