LAT2 Protein (His tag)

Produktnummer ABIN7318738

Produktdetails

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses LAT2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human LAT2 Protein (His Tag)

Sequenz: Arg27-Ala243

Produktmerkmale: Recombinant Human Linker for Activation of T-Cells Family Member 2 is produced by our Mammalian expression system and the target gene encoding Arg27-Ala243 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Andere Bezeichnung: LAT2 (LAT2 Produkte)

Synonyme: LAB Protein, NTAL Protein, WBSCR15 Protein, WBSCR5 Protein, WSCR5 Protein, LAT2 Protein, MGC139435 Protein, Ntal Protein, Wbscr5 Protein, AW125574 Protein, Wbscr15 Protein, linker for activation of T-cells family member 2 Protein, linker for activation of T cells family, member 2 Protein, LAT2 Protein, Lat2 Protein

Hintergrund:

Background: Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Synonym: Linker for Activation of T-Cells Family Member 2, Linker for Activation of B-Cells, Membrane-Associated Adapter Molecule, Non-T-Cell Activation Linker, Williams-Beuren Syndrome Chromosomal Region 15 Protein, Williams-Beuren Syndrome Chromosomal Region 5 Protein, LAT2, LAB, NTAL, WBS15, WBSCR15, WBSCR5

Molekulargewicht: 25.0 kDa

UniProt: Q9GZY6

Pathways: Fc-epsilon Rezeptor Signalübertragung, BCR Signaling