Cyclin H Protein (CCNH) (AA 1-323) (His tag)

Produktnummer ABIN666973

Produktdetails

Target: Cyclin H (CCNH)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-323

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Cyclin H Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Cyclin H, 1- 323 aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 30% glycerol, 2mM EDTA, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: Cyclin H (CCNH)

Andere Bezeichnung: Cyclin H (CCNH Produkte)

Synonyme: zgc:114132 Protein, cak Protein, p34 Protein, p37 Protein, Cych Protein, ACYPI004637 Protein, ccnh Protein, Cyclin-H Protein, 142767_at Protein, CG7405 Protein, Dmel\\CG7405 Protein, CAK Protein, 6330408H09Rik Protein, AI661354 Protein, AV102684 Protein, AW538719 Protein, ccnh-A Protein, cyclin H Protein, cyclin-H Protein, Cyclin H Protein, CYclin H Protein, cyclin H L homeolog Protein, CCNH Protein, ccnh Protein, LOC5577539 Protein, Cych Protein, CycH Protein, cyh-1 Protein, Ccnh Protein, ccnh.L Protein

Hintergrund: Cyclin H, also known as CDK7, is a member of the cyclin-dependent protein kinase family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). Cyclin H is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. Recombinant human Cyclin H, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CCNH, CAK, p34, p37, 6330408H09Rik, AI661354, AV102684, AW538719, CDK activating kinase, Cyclin dependent kinase activating kinase, Cyclin H, CyclinH, MO15 associated protein, P36, Cyclin-H. NCBI no.: NP_001230

Molekulargewicht: 39.8 kDa (343aa), confirmed by MALDI-TOF

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase