IL7R Protein (AA 21-239) (hIgG-His-tag)

Produktnummer ABIN6388135

Produktdetails

Target: IL7R (Interleukin 7 Receptor (IL7R))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-239

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses IL7R Protein ist gelabelt mit hIgG-His-tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADLESGYAQN GDLEDAELDD YSFSCYSQLE VNGSQHSLTC AFEDPDVNIT NLEFEICGAL VEVKCLNFRK LQEIYFIETK KFLLIGKSNI CVKVGEKSLT CKKIDLTTIV KPEAPFDLSV VYREGANDFV VTFNTSHLQK KYVKVLMHDV AYRQEKDENK WTHVNLSSTK LTLLQRKLQP AAMYEIKVRS IPDHYFKGFW SEWSPSYYFR TPEINNSSGE MDLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

Reinheit: > 90 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: IL7R (Interleukin 7 Receptor (IL7R))

Andere Bezeichnung: IL7R (IL7R Produkte)

Synonyme: IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein

Hintergrund: IL7R, also known as interleukin-7 receptor, is a hematopoietin receptor superfamily member. It plays important role in lymphocyte differentiation, proliferation, multiple sclerosis, and survival. This protein signaling is essential for T-cell development and regulation of native and memory T-cell homeostasis. Also, it is critically required for the proper development and function of lymphoid cells. Recombinant human IL7R, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 52.5kDa (461aa) 50-70kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_002176

UniProt: P16871

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size