IL7R Protein (Fc Tag)
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- Target Alle IL7R Proteine anzeigen
- IL7R (Interleukin 7 Receptor (IL7R))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL7R Protein ist gelabelt mit Fc Tag.
- Sequenz
- Glu21-Gly236
- Reinheit
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-7 at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 0.21μg/ml determined by ELISA. See testing image for detail.
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Interleukin 7 Receptor (IL7R) (AA 21-239) protein (Fc Tag)
IL7R Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 7 Receptor (IL7R) protein (His tag)IL7R Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 7 Receptor (IL7R) (AA 21-236) (Active) protein (Fc Tag)IL7R Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 7 Receptor (IL7R) (Active) protein (Fc Tag)IL7R Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 7 Receptor (IL7R) (Active) protein (Fc Tag)IL7R Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 7 Receptor (IL7R) (AA 1-459) protein (GST tag)IL7R Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 7 Receptor (IL7R) protein (His tag)IL7R Spezies: Maus Wirt: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Interleukin 7 Receptor (IL7R) (AA 21-239) protein (His tag)Crystallography grade IL7R Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 7 Receptor (IL7R) (AA 265-459) protein (His tag)Crystallography grade IL7R Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 7 Receptor (IL7R) (AA 21-239) protein (His tag)Crystallography grade IL7R Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Andere Bezeichnung
- IL-7R alpha (IL7R Produkte)
- Synonyme
- IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
- Hintergrund
- IL-17R alpha, IL7Ra, CD127, CDW127, ILRA,Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.
- Molekulargewicht
- 51.6 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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