CDC25A Protein (AA 1-524) (His tag)

Produktnummer ABIN6386706

Produktdetails

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-524

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CDC25A Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: CDC25A, 1-524aa, Human, His tag, E.coli

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 0.2M NaCl, 1mM EDTA

Lagerung: 4 °C

Antigendetails

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Andere Bezeichnung: CDC25A (CDC25A Produkte)

Synonyme: cdc25a2 Protein, cdc25A Protein, sb:cb317 Protein, CDC25A2 Protein, D9Ertd393e Protein, cell division cycle 25A Protein, cell division cycle 25B Protein, cell division cycle 25A S homeolog Protein, CDC25A Protein, cdc25a Protein, cdc25b Protein, Cdc25a Protein, cdc25a.S Protein

Hintergrund: M-phase inducer phosphatase 1, also known as CDC25A, is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Recombinant human CDC25A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A, Cdc 25a, Cell division cycle 25 homolog A (S. pombe), Cell division cycle 25A, Cell division cycle 25A isoform a, Cell division cycle 25A isoform b, D9Ertd393e, EC 3.1.3.48, M phase inducer phosphatase 1, MGC115549. NCBI no.: NP_001780

Molekulargewicht: 63.2 kDa (560aa)

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase