TNFSF4 Protein (AA 51-183) (Fc Tag)

Produktnummer ABIN6253372

Produktdetails

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 51-183

Spezies: Human, Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TNFSF4 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: CD252 [OX40L] (human):Fc (mouse) (rec.)

Spezifität: The extracellular domain of human CD252 (aa 51-183) is fused to the N-terminus of the Fc region of mouse IgG2a.

Produktmerkmale: Protein. The extracellular domain of human CD252 (aa 51-183) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: HEK 293 cells. Endotoxin content: <5EU/mg purified protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.

Reinheit: >98 % (SDS-PAGE)

Endotoxin-Niveau: <5EU/mg purified protein (LAL test, Lonza).

Biological Activity Comment: Measured by its binding ability in a functional ELISA.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from 0.2μm-filtered solution in PBS.

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Antigendetails

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Andere Bezeichnung: CD252 [OX40L] (TNFSF4 Produkte)

Synonyme: TNFSF4 Protein, OX40L Protein, TNFRSF4 Protein, CD134L Protein, CD252 Protein, GP34 Protein, OX-40L Protein, OX4OL Protein, TXGP1 Protein, Ath-1 Protein, Ath1 Protein, Ox40l Protein, Txgp1l Protein, gp34 Protein, TNF superfamily member 4 Protein, tumor necrosis factor (ligand) superfamily, member 4 Protein, TNFSF4 Protein, Tnfsf4 Protein

Hintergrund:

Alternate Names/Synonyms: TNFSF4

Product Description: OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.

Molekulargewicht: ~55kDa (SDS-PAGE)

NCBI Accession: NP_003317

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints