Ephrin B3 Protein (EFNB3) (AA 28-226) (His tag)

Produktnummer ABIN5854779

Produktdetails

Target: Ephrin B3 (EFNB3)

Protein-Typ: Recombinant

Proteineigenschaft: AA 28-226

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses Ephrin B3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPLSLEPVY WNSANKRFQA EGGYVLYPQI GDRLDLLCPR ARPPGPHSSP NYEFYKLYLV GGAQGRRCEA PPAPNLLLTC DRPDLDLRFT IKFQEYSPNL WGHEFRSHHD YYIIATSDGT REGLESLQGG VCLTRGMKVL LRVGQSPRGG AVPRKPVSEM PMERDRGAAH SLEPGKENLP GDPTSNATSR GAEGPLPPPS MPHHHHHH

Reinheit: > 95 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Ephrin B3 (EFNB3)

Andere Bezeichnung: EFNB3 (EFNB3 Produkte)

Synonyme: efnb3-A Protein, EphB3 Protein, EFNB3 Protein, efnb3 Protein, id:ibd5049 Protein, zgc:111938 Protein, EFL-6 Protein, ELF-3 Protein, Elk-L3 Protein, Epl8 Protein, LERK-8 Protein, NLERK-2 Protein, ELK-L3 Protein, RGD1565678 Protein, EFL6 Protein, EPLG8 Protein, LERK8 Protein, ephrin B3 Protein, ephrin-B3 L homeolog Protein, ephrin-B3b Protein, ephrin-B3 Protein, EFNB3 Protein, efnb3.L Protein, efnb3b Protein, efnb3 Protein, Efnb3 Protein

Hintergrund: EFNB3, also known as ephrin-B3, is a member of the Ephrin-B family of transmembrane ligands that bind and induce the tyrosine autophosphorylation of Eph receptors. EFNB3 is expressed on oligodendrocytes and neurons in the hippocampus and along the midline of the spinal cord. It is up-regulated in glioma and promotes tumor cell invasion and migration. This protein acts as the midline barrier that prevents corticospinal tract projections from recrossing when they enter the spinal gray matter. Recombinant human EFNB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 23.0kDa (208aa) 28-40KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_001397

UniProt: Q15768

Pathways: RTK Signalweg