Ephrin B3 Protein (EFNB3) (AA 28-227) (His tag)

Produktnummer ABIN5709447

Recombinant Ephrin B3-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Ephrin B3 Protein (EFNB3) (AA 28-227) (His tag) (ABIN5709447)

Target: Ephrin B3 (EFNB3)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 28-227

Aufreinigungstag / Konjugat: Dieses Ephrin B3 Protein ist gelabelt mit His tag.

Sequenz: LSLEPVYWNS ANKRFQAEGG YVLYPQIGDR LDLLCPRARP PGPHSSPSYE FYKLYLVEGA QGRRCEAPPA PNLLLTCDRP DLDLRFTIKF QEYSPNLWGH EFRSHHDYYI IATSDGTREG LESLQGGVCL TRGMKVLLRV GQSPRGGAVP RKPVSEMPME RDRGAAHSAE PGRDTIPGDP SSNATSRGAE GPLPPPSMPA

Aufreinigung: SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Ephrin B3 (EFNB3)

Andere Bezeichnung: EFNB3

Hintergrund: Cell surface transmbrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.

Molekulargewicht: 26.1 kDa

UniProt: O35393

Pathways: RTK Signalweg