VTCN1 Protein (AA 26-258, partial) (His tag)

Produktnummer ABIN5712834

Produktdetails

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Protein-Typ: Recombinant

Proteineigenschaft: partial, AA 26-258

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses VTCN1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: IIGFGISGRH SITVTTVASA GNIGEDGILS CTFEPDIKLS DIVIQWLKEG VLGLVHEFKE GKDELSEQDE MFRGRTAVFA DQVIVGNASL RLKNVQLTDA GTYKCYIITS KGKGNANLEY KTGAFSMPEV NVDYNASSET LRCEAPRWFP QPTVVWASQV DQGANFSEVS NTSFELNSEN VTMKVVSVLY NVTINNTYSC MIENDIAKAT GDIKVTESEI KRRSHLQLLN SKA

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Andere Bezeichnung: VTCN1 (VTCN1 Produkte)

Synonyme: B7h4 Protein, B7s1 Protein, B7x Protein, BC032925 Protein, B7-H4 Protein, B7H4 Protein, B7S1 Protein, B7X Protein, B7h.5 Protein, PRO1291 Protein, VCTN1 Protein, RGD1311204 Protein, V set domain containing T cell activation inhibitor 1 L homeolog Protein, V-set domain containing T cell activation inhibitor 1 Protein, V-set domain containing T-cell activation inhibitor 1 Protein, V set domain containing T cell activation inhibitor 1 Protein, vtcn1.L Protein, VTCN1 Protein, vtcn1 Protein, Vtcn1 Protein

Hintergrund: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Molekulargewicht: 29.7 kDa

UniProt: Q7Z7D3