TWEAK Protein (AA 43-149) (His-SUMO Tag)
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- Target Alle TWEAK (TNFSF12) Proteine anzeigen
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 43-149
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses TWEAK Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- SLGSRASLSA QEPAQEELVA EEDQDPSELN PQTEESQDPA PFLNRLVRPR RSAPKGRKTR ARRAIAAHYE VHPRPGQDGA QAGVDGTVSG WEEARINSSS PLRYNRQIGE FIVTRAGLYY LYCQVHFDEG KAVYLKLDLL VDGVLALRCL EEFSATAASS LGPQLRLCQV SGLLALRPGS SLRIRTLPWA HLKAAPFLTY FGLFQVH
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product TNFSF12 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Andere Bezeichnung
- TNF12 (TNFSF12 Produkte)
- Synonyme
- APO3L Protein, DR3LG Protein, TWEAK Protein, Apo3l Protein, Dr3l Protein, Dr3lg Protein, Tweak Protein, TNF superfamily member 12 Protein, tumor necrosis factor (ligand) superfamily, member 12 Protein, TNFSF12 Protein, Tnfsf12 Protein
- Hintergrund
- Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
- Molekulargewicht
- 38.85 kDa
- UniProt
- O43508
- Pathways
- Apoptose
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