TWEAK Produkte
(Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
Kategorien
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010].
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Ausgewählte TWEAK Kategorien
TWEAK Antikörper
High quality antibodies with extensive validation data.
TWEAK ELISA Kits
Reliable ELISA kits for a wide range of species.
TWEAK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TWEAK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN6149339
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6265650
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC
Validierungen
- (3)
Kat. Nr.
ABIN7261608
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene TWEAK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6962633
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970936
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960250
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TWEAK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275763
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293T Cells
Validierungen
- (2)
Kat. Nr.
ABIN4369884
Menge
2 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323218
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TWEAK Produkten
: "Serum tumor necrosis factor-like weak inducer of apoptosis levels are elevated in schizophrenia." in: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), (2020) (PubMed).: "The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury." in: Kidney international, Vol. 89, Issue 2, pp. 399-410, (2016) (PubMed).
: "TWEAK protects cardiomyocyte against apoptosis in a PI3K/AKT pathway dependent manner." in: American journal of translational research, Vol. 8, Issue 9, pp. 3848-3860, (2016) (PubMed).
: "Increased serum tumor necrosis factor receptor-associated factor-6 expression in patients with non-metastatic triple-negative breast cancer." in: Oncology letters, Vol. 9, Issue 6, pp. 2819-2824, (2015) (PubMed).
: "Therapeutic targeting of TWEAK/Fnl4 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway." in: Results and problems in cell differentiation, Vol. 49, pp. 145-60, (2010) (PubMed).
: "Fibroblast growth factor-inducible 14 (Fn14) is expressed in the lower genital tract and may play a role in amplifying inflammation during infection." in: Journal of reproductive immunology, Vol. 84, Issue 1, pp. 16-23, (2010) (PubMed).
: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).
: "TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF." in: Biochemical and biophysical research communications, Vol. 318, Issue 2, pp. 422-7, (2004) (PubMed).
: "The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 6020-9, (2002) (PubMed).
: "Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity." in: The Journal of experimental medicine, Vol. 192, Issue 9, pp. 1373-80, (2000) (PubMed).
Synonyme und alternative Namen zu TWEAK
TNF superfamily member 12 (TNFSF12), tumor necrosis factor (ligand) superfamily, member 12 (TNFSF12), tumor necrosis factor (ligand) superfamily, member 12 (Tnfsf12), TNF superfamily member 12 (Tnfsf12), APO3L, Apo3l, Dr3l, DR3LG, Dr3lg, TWEAK, TweakBezeichner auf Proteinebene für TWEAK
- APO3 ligand
- APO3/DR3 ligand
- TNF-related WEAK inducer of apoptosis
- tumor necrosis factor ligand superfamily member 12
- tumor necrosis factor superfamily member 12
- TNF-related weak inducer of apoptosis
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