TNFSF9
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
Protein-Typ
Recombinant
Biologische Aktivität
Active
Proteineigenschaft
AA 104-309
Spezies
Maus
Quelle
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses TNFSF9 Protein ist gelabelt mit Fc Tag.
Sequenz
AA 104-309
Produktmerkmale
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
TNFSF9
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.