IRF3 Protein (GST tag)
(4 Referenzen)-
- Target Alle IRF3 Proteine anzeigen
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Protein-Typ
- Recombinant
-
Spezies
- Human
-
Quelle
- Wheat germ
- Aufreinigungstag / Konjugat
- Dieses IRF3 Protein ist gelabelt mit GST tag.
- Applikation
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- Verwendungszweck
- IRF3 (Human) Recombinant Protein (P01)
- Sequenz
- MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALSRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT PFPNLGPSEN PLKRLLVPGE EWEFEVTAFY RGRQVFQQTI SCPEGLRLVG SEVGDRTLPG WPVTLPDPGM SLTDRGVMSY VRHVLSCLGG GLALWRAGQW LWAQRLGHCH TYWAVSEELL PNSGHGPDGE VPKGKEGGVF DLGPFIVGSW APRSDYLHGR KRTLTTLCPL VLCGGVMAPG PAVDQEARDG QGCAHVPQGL GRNGPGRGCL LPGEYCGPAH FQQPPTLPHL RPVQGLPAGL GGGHGFPGPW GDLSPRSSWC ASNPPVPHHL NQ
- Produktmerkmale
- Human IRF3 full-length ORF ( AAH09395, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.
- Aufreinigung
- in vitro wheat germ expression system
-
Interferon Regulatory Factor 3 (IRF3) (AA 2-427) protein (His tag)
IRF3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interferon Regulatory Factor 3 (IRF3) (AA 1-427) protein (GST tag)IRF3 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 3 (IRF3) (AA 1-419) protein (Strep Tag)Crystallography grade IRF3 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interferon Regulatory Factor 3 (IRF3) (AA 1-427) protein (Strep Tag)Crystallography grade IRF3 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interferon Regulatory Factor 3 (IRF3) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)IRF3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Handhabung
- Aliquot to avoid repeated freezing and thawing.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Best use within three months from the date of receipt of this protein.
-
-
: "The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." in: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).
: "Quantitation of the dynamic profiles of the innate immune response using multiplex selected reaction monitoring-mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1513-29, (2013) (PubMed).
: "NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses." in: PLoS ONE, Vol. 7, Issue 9, pp. e43756, (2012) (PubMed).
: "Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16202-9, (2009) (PubMed).
-
: "The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." in: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).
-
- Target
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Andere Bezeichnung
- IRF3 (IRF3 Produkte)
- Synonyme
- irf3 Protein, IRF3 Protein, C920001K05Rik Protein, IRF-3 Protein, interferon regulatory factor 3 Protein, interferon regulatory factor 7 Protein, irf3 Protein, IRF3 Protein, irf-3 Protein, Irf3 Protein, IRF7 Protein
- Hintergrund
- Gene: interferon regulatory factor 3
- Gen-ID
- 3661
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
-
