XRCC6 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735700

Produktdetails

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses XRCC6 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human XRCC6 / Ku70 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Andere Bezeichnung: Xrcc6,ku70 (XRCC6 Produkte)

Synonyme: CTC75 Protein, CTCBF Protein, G22P1 Protein, KU70 Protein, ML8 Protein, TLAA Protein, 70kDa Protein, G22p1 Protein, Ku70 Protein, Kup70 Protein, X-ray repair cross complementing 6 Protein, ATP-dependent DNA helicase II, 70 kDa subunit Protein, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog Protein, X-ray repair complementing defective repair in Chinese hamster cells 6 Protein, XRCC6 Protein, Bm1_41430 Protein, xrcc6.L Protein, Xrcc6 Protein

Hintergrund: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Molekulargewicht: 69.7 kDa

NCBI Accession: NP_001460

Pathways: DNA Reparatur