TPP1 Protein (His tag)

Produktnummer ABIN2734312

Produktdetails

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TPP1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Tripeptidyl-peptidase 1 (TPP1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Supplied as a 0.2 μM filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Andere Bezeichnung: Tripeptidyl-Peptidase 1 (Tpp1) (TPP1 Produkte)

Synonyme: cln2 Protein, fa01b09 Protein, im:7149243 Protein, wu:fa01b09 Protein, CLN2 Protein, LPIC Protein, TPP-1 Protein, TPP-I Protein, Cln2 Protein, tripeptidyl peptidase I Protein, tripeptidyl-peptidase 1 Protein, tripeptidyl peptidase 1 Protein, tpp1 Protein, NAEGRDRAFT_78259 Protein, MCYG_00184 Protein, MGYG_05881 Protein, MGYG_00757 Protein, TPP1 Protein, Tpp1 Protein

Hintergrund: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Molekulargewicht: 23.94kD

NCBI Accession: NP_000382

Pathways: Zellzyklus, ER-Nucleus Signaling