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TPP1 Protein (His tag)

TPP1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319430
  • Target Alle TPP1 Proteine anzeigen
    TPP1 (Tripeptidyl Peptidase I (TPP1))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses TPP1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human TPP1/CLN2 Protein (His Tag)
    Sequenz
    Ser20-Pro563
    Produktmerkmale
    Recombinant Human TPP1 is produced by our Mammalian expression system and the target gene encoding Ser20-Pro563 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TPP1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    TPP1 (Tripeptidyl Peptidase I (TPP1))
    Andere Bezeichnung
    TPP1/CLN2 (TPP1 Produkte)
    Synonyme
    cln2 Protein, fa01b09 Protein, im:7149243 Protein, wu:fa01b09 Protein, CLN2 Protein, LPIC Protein, TPP-1 Protein, TPP-I Protein, Cln2 Protein, tripeptidyl peptidase I Protein, tripeptidyl-peptidase 1 Protein, tripeptidyl peptidase 1 Protein, tpp1 Protein, NAEGRDRAFT_78259 Protein, MCYG_00184 Protein, MGYG_05881 Protein, MGYG_00757 Protein, TPP1 Protein, Tpp1 Protein
    Hintergrund

    Background: Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).

    Synonym: Tripeptidyl-Peptidase 1, TPP-1, Cell Growth-Inhibiting Gene 1 Protein, Lysosomal Pepstatin-Insensitive Protease, LPIC, Tripeptidyl Aminopeptidase, TPP1, CLN2,GIG1,LPIC,SCAR7,TPP-1

    Molekulargewicht
    60.35 kDa
    UniProt
    O14773
    Pathways
    Zellzyklus, ER-Nucleus Signaling
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