TCF4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2733361

Produktdetails

Target: TCF4 (Transcription Factor 4 (TCF4))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TCF4 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TCF4 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TCF4 (Transcription Factor 4 (TCF4))

Andere Bezeichnung: Tcf4 (TCF4 Produkte)

Synonyme: E2-2 Protein, ITF-2 Protein, ITF2 Protein, PTHS Protein, SEF-2 Protein, SEF2 Protein, SEF2-1 Protein, SEF2-1A Protein, SEF2-1B Protein, TCF-4 Protein, bHLHb19 Protein, 5730422P05Rik Protein, ASP-I2 Protein, E2.2 Protein, ITF-2b Protein, ME2 Protein, MITF-2A Protein, MITF-2B Protein, TFE Protein, Tcf-4 Protein, TCF7L2 Protein, XE2 Protein, Xtcf-4 Protein, Xtcf4 Protein, e2-A Protein, tcf-4 Protein, transcription factor 4 Protein, transcription factor 4 S homeolog Protein, TCF4 Protein, Tcf4 Protein, tcf4 Protein, tcf4.S Protein

Hintergrund: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to > 50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

Molekulargewicht: 71.1 kDa

NCBI Accession: NP_003190

Pathways: WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus