SOCS1 Protein (Myc-DYKDDDDK Tag)
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- Target Alle SOCS1 Proteine anzeigen
- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SOCS1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human SOCS1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SOCS1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
- Andere Bezeichnung
- Socs1 (SOCS1 Produkte)
- Synonyme
- socs1 Protein, zgc:91868 Protein, jab Protein, cis1 Protein, ssi1 Protein, tip3 Protein, cish1 Protein, ssi-1 Protein, socs-1 Protein, SOCS1 Protein, LOC100228306 Protein, socs1b Protein, CIS1 Protein, CISH1 Protein, JAB Protein, SOCS-1 Protein, SSI-1 Protein, SSI1 Protein, TIP3 Protein, Cish1 Protein, Cish7 Protein, Socs-1 Protein, suppressor of cytokine signaling 1a Protein, suppressor of cytokine signaling 1 Protein, suppressor of cytokine signaling 1 L homeolog Protein, socs1a Protein, socs1 Protein, SOCS1 Protein, socs1.L Protein, Socs1 Protein
- Hintergrund
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
- Molekulargewicht
- 23.4 kDa
- NCBI Accession
- NP_003736
- Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, TLR Signalweg, Response to Growth Hormone Stimulus
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