PAI1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2731824

Produktdetails

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PAI1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SERPINE1 / PAI1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Andere Bezeichnung: Serpine1,pai1 (SERPINE1 Produkte)

Synonyme: PAI Protein, PAI-1 Protein, PAI1 Protein, PLANH1 Protein, SERPINE1 Protein, si:ch211-138a11.1 Protein, Planh1 Protein, PAI1A Protein, Pai1 Protein, Pai1aa Protein, Planh Protein, RATPAI1A Protein, serpin family E member 1 Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Protein, serine (or cysteine) peptidase inhibitor, clade E, member 1 Protein, SERPINE1 Protein, serpine1.L Protein, serpine1 Protein, Serpine1 Protein

Hintergrund: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 42.7 kDa

NCBI Accession: NP_000593

Pathways: p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration