PAI1 Protein (AA 24-402) (His tag)

Produktnummer ABIN1691566

Produktdetails

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 24-402

Spezies: Maus

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses PAI1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Plasminogen Activator Inhibitor 1/PAI-1/SERPIN E1 (C-6His)

Sequenz: LPLRESHTAH QATDFGVKVF QQVVQASKDR NVVFSPYGVS SVLAMLQMTT AGKTRRQIQD AMGFKVNEKG TAHALRQLSK ELMGPWNKNE ISTADAIFVQ RDLELVQGFM PHFFKLFQTM VKQVDFSEVE RARFIINDWV ERHTKGMISD LLAKGAVDEL TRLVLVNALY FSGQWKTPFL EASTHQRLFH KSDGSTVSVP MMAQSNKFNY TEFTTPDGLE YDVVELPYQG DTLSMFIAAP FEKDVHLSAL TNILDAELIR QWKGNMTRLP RLLILPKFSL ETEVDLRGPL EKLGMPDMFS ATLADFTSLS DQEQLSVAQA LQKVRIEVNE SGTVASSSTA FVISARMAPT EMVIDRSFLF VVRHNPTETI LFMGQVMEPV DHHHHHH

Produktmerkmale: Recombinant Mouse Plasminogen activator inhibitor 1/SERPIN E1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu24-Ser402) of Mouse SERPIN E1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 5 months

Antigendetails

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Andere Bezeichnung: SERPIN E1 (SERPINE1 Produkte)

Synonyme: PAI Protein, PAI-1 Protein, PAI1 Protein, PLANH1 Protein, SERPINE1 Protein, si:ch211-138a11.1 Protein, Planh1 Protein, PAI1A Protein, Pai1 Protein, Pai1aa Protein, Planh Protein, RATPAI1A Protein, serpin family E member 1 Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Protein, serine (or cysteine) peptidase inhibitor, clade E, member 1 Protein, SERPINE1 Protein, serpine1.L Protein, serpine1 Protein, Serpine1 Protein

Sub Type: Fusionprotein

Hintergrund: Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
Alternative Names: Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1, Mr1, Pai1, Planh1,

Molekulargewicht: 43.7 kDa

UniProt: P22777

Pathways: p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration