NFATC1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target Alle NFATC1 Proteine anzeigen
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 1
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses NFATC1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human NFAT2 / NFATC (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFATC1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Andere Bezeichnung
- Nfat2,nfatc (NFATC1 Produkte)
- Synonyme
- nf-atc Protein, nfat2 Protein, nfatc Protein, si:ch211-198c22.2 Protein, NFATC1 Protein, 2210017P03Rik Protein, AI449492 Protein, AV076380 Protein, NF-ATc Protein, NFAT2 Protein, NFATc Protein, Nfatcb Protein, NF-ATC Protein, NF-ATc1 Protein, NFAT Protein, NFATmac Protein, nuclear factor of activated T-cells 1 Protein, nuclear factor of activated T-cells 1 L homeolog Protein, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 Protein, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 Protein, NFATC1 Protein, nfatc1.L Protein, nfatc1 Protein, Nfatc1 Protein
- Hintergrund
- The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
- Molekulargewicht
- 77.6 kDa
- NCBI Accession
- NP_765978
- Pathways
- RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung
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