IDH2 Protein (DYKDDDDK Tag)
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- Target Alle IDH2 Proteine anzeigen
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Insect cells (Sf9)
- Aufreinigungstag / Konjugat
- Dieses IDH2 Protein ist gelabelt mit DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Isocitrate dehydrogenase / IDH2 protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IDH2 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- Andere Bezeichnung
- Isocitrate Dehydrogenase,idh2 (IDH2 Produkte)
- Synonyme
- F6P23.14 Protein, F6P23_14 Protein, IDH-II Protein, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 Protein, isocitrate dehydrogenase II Protein, isocitrate dehydrogenase subunit 2 Protein, D2HGA2 Protein, ICD-M Protein, IDH Protein, IDHM Protein, IDP Protein, IDPM Protein, mNADP-IDH Protein, E430004F23 Protein, IDPm Protein, Idh-2 Protein, wu:fb33c06 Protein, wu:fk31e05 Protein, wu:fq43b01 Protein, zgc:55485 Protein, idh2 Protein, IDH2 Protein, isocitrate dehydrogenase subunit 2 Protein, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial Protein, isocitrate dehydrogenase 2 (NADP+), mitochondrial Protein, isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog Protein, isocitrate dehydrogenase [NADP], mitochondrial Protein, IDH2 Protein, Idh2 Protein, idh2.S Protein, idh2 Protein, LOC100441867 Protein
- Hintergrund
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
- Molekulargewicht
- 46.6 kDa
- NCBI Accession
- NP_002159
- Pathways
- Warburg Effekt
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