IRAK3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723783

Produktdetails

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IRAK3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human IRAK3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Andere Bezeichnung: Irak3 (IRAK3 Produkte)

Synonyme: IRAK3 Protein, si:dkey-150i15.2 Protein, ASRT5 Protein, IRAKM Protein, IrakM Protein, 4833428C18Rik Protein, AI563835 Protein, IRAK-M Protein, interleukin 1 receptor associated kinase 3 Protein, interleukin-1 receptor-associated kinase 3 Protein, IRAK3 Protein, irak3 Protein, Irak3 Protein

Hintergrund: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 67.6 kDa

NCBI Accession: NP_009130

Pathways: TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades