ING1 Protein (His tag)
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- Target Alle ING1 Proteine anzeigen
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses ING1 Protein ist gelabelt mit His tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human ING1 (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ING1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the N-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
- Andere Bezeichnung
- Ing1 (ING1 Produkte)
- Synonyme
- p24ING1c Protein, p33 Protein, p33ING1 Protein, p33ING1b Protein, p47 Protein, p47ING1a Protein, p33ING1c Protein, zgc:136918 Protein, ING1 Protein, 2610028J21Rik Protein, AA407184 Protein, AI875420 Protein, mING1h Protein, p33Ing1 Protein, p37Ing1b Protein, xing1 Protein, inhibitor of growth family member 1 Protein, inhibitor of growth family, member 1 Protein, inhibitor of growth family member 1 S homeolog Protein, ING1 Protein, Ing1 Protein, ing1 Protein, ing1.S Protein
- Hintergrund
- This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Molekulargewicht
- 23.5 kDa
- NCBI Accession
- NP_937861
- Pathways
- Protein targeting to Nucleus, Autophagie
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