ING1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723440

Produktdetails

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ING1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ING1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Andere Bezeichnung: Ing1 (ING1 Produkte)

Synonyme: p24ING1c Protein, p33 Protein, p33ING1 Protein, p33ING1b Protein, p47 Protein, p47ING1a Protein, p33ING1c Protein, zgc:136918 Protein, ING1 Protein, 2610028J21Rik Protein, AA407184 Protein, AI875420 Protein, mING1h Protein, p33Ing1 Protein, p37Ing1b Protein, xing1 Protein, inhibitor of growth family member 1 Protein, inhibitor of growth family, member 1 Protein, inhibitor of growth family member 1 S homeolog Protein, ING1 Protein, Ing1 Protein, ing1 Protein, ing1.S Protein

Hintergrund: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 31.7 kDa

NCBI Accession: NP_937862

Pathways: Protein targeting to Nucleus, Autophagie