IKKi/IKKe Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723361

Produktdetails

Target: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IKKi/IKKe Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human IKBKE / IKKE protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Andere Bezeichnung: Ikbke,ikke (IKBKE Produkte)

Synonyme: zgc:100844 Protein, IKBKE Protein, MGC130907 Protein, IKK-E Protein, IKK-i Protein, IKKE Protein, IKKI Protein, AW558201 Protein, IKKepsilon Protein, Ikki Protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon Protein, inhibitor of nuclear factor kappa B kinase subunit epsilon Protein, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog Protein, inhibitor of kappaB kinase epsilon Protein, IKBKE Protein, ikbke Protein, ikbke.L Protein, Ikbke Protein

Hintergrund: IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009].

Molekulargewicht: 80.3 kDa

NCBI Accession: NP_054721

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades