XIAP Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723210

Produktdetails

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses XIAP Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human IAP3 / BIRC4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Andere Bezeichnung: Iap3,birc4 (XIAP Produkte)

Synonyme: API3 Protein, BIRC4 Protein, IAP-3 Protein, ILP1 Protein, MIHA Protein, XLP2 Protein, hIAP-3 Protein, hIAP3 Protein, api3 Protein, birc4 Protein, ilp1 Protein, miha Protein, xlp2 Protein, xxiap Protein, 1110015C02Rik Protein, Aipa Protein, Api3 Protein, Birc4 Protein, IAP3 Protein, ILP-1 Protein, mXIAP Protein, riap3 Protein, fb73d01 Protein, wu:fb73d01 Protein, zgc:91873 Protein, BIRC8 Protein, X-linked inhibitor of apoptosis Protein, X-linked inhibitor of apoptosis L homeolog Protein, XIAP Protein, xiap Protein, xiap.L Protein, Xiap Protein

Hintergrund: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011].

Molekulargewicht: 56.5 kDa

NCBI Accession: NP_001158

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Transition Metal Ion Homeostasis