BIRC3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723207

Produktdetails

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BIRC3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human IAP1 / BIRC3 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Andere Bezeichnung: Iap1,birc3 (BIRC3 Produkte)

Synonyme: AIP1 Protein, API2 Protein, CIAP2 Protein, HAIP1 Protein, HIAP1 Protein, MALT2 Protein, MIHC Protein, RNF49 Protein, c-IAP2 Protein, Api1 Protein, Api2 Protein, IAP1 Protein, IAP2 Protein, MIHB Protein, Birc2 Protein, HIAP2 Protein, MIAP1 Protein, MIAP2 Protein, cIAP1 Protein, cIAP2 Protein, cIAP-1 Protein, cIAP-2 Protein, AW107670 Protein, BIRC2 Protein, baculoviral IAP repeat containing 3 Protein, baculoviral IAP repeat-containing 3 Protein, baculoviral IAP repeat-containing protein 3 Protein, inhibitor of apoptosis protein-2 Protein, BIRC3 Protein, Birc3 Protein, LOC100399118 Protein, OpmnVgp074 Protein

Hintergrund: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Molekulargewicht: 68.2 kDa

NCBI Accession: NP_892007

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades