BTK Protein (His tag)

Produktnummer ABIN2715351

Produktdetails

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Insect cells (Sf9)

Aufreinigungstag / Konjugat: Dieses BTK Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human BTK (full length, C-term polyhistidine tag) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Andere Bezeichnung: Btk (BTK Produkte)

Synonyme: BTK Protein, atk Protein, bpk Protein, xla Protein, imd1 Protein, agmx1 Protein, psctk1 Protein, AGMX1 Protein, AT Protein, ATK Protein, BPK Protein, IMD1 Protein, PSCTK1 Protein, XLA Protein, AI528679 Protein, xid Protein, Bruton tyrosine kinase Protein, Bruton agammaglobulinemia tyrosine kinase Protein, BTK Protein, btk Protein, Btk Protein

Hintergrund: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 76 kDa

NCBI Accession: NP_000052

Pathways: Fc-epsilon Rezeptor Signalübertragung, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling