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IL-3 Protein (AA 27-166) (His tag)

IL-3 Spezies: Ratte Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Produktnummer ABIN2018105
  • Target Alle IL-3 Proteine anzeigen
    IL-3 (Interleukin 3 (IL-3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 27-166
    Spezies
    • 26
    • 14
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Quelle
    • 31
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    CHO Cells
    Aufreinigungstag / Konjugat
    Dieses IL-3 Protein ist gelabelt mit His tag.
    Produktmerkmale
    ED50 < 8 ng/mL, measured in a cell proliferation assay using NF S-60 cells.
    AA 27-166, expressed with C-terminal 6xHis.
    Reinheit
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL-3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant ratInterleukin-3 (IL-3), His remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rat Interleukin-3 (IL-3), His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    IL-3 (Interleukin 3 (IL-3))
    Andere Bezeichnung
    Interleukin-3 (IL-3) (IL-3 Produkte)
    Synonyme
    BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
    Hintergrund
    Interleukin-3 (IL-3), also known as MCGF, Multi-CSF, HCGF and P-cell stimulation factor, belongs tothe alpha-helixfamily of hematopoietic cytokines. It is produced by activated T-cells, mast cells and natural killer cells. IL-3 binds to the IL-3 receptor alpha subunit and recruits the signal-transducing common beta chain. IL-3induced signal transduction results in the survival, differentiation and proliferation of a variety of immune cells, such as macrophages, neutrophils, megakaryocytes, mast cells and hematopoietic stem cells. IL-3 often acts synergistically with other cytokines, such as IL-7, EPO, GM-CSF and IL-6, to exert its simulative function.
    Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
    Molekulargewicht
    22-34 kDa, observed by reducing SDS-PAGE.
    UniProt
    P04823
    Pathways
    JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
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