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IRF5 Protein (AA 1-498) (His tag)

IRF5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >90% by SDS-PAGE
Produktnummer ABIN1691985
  • Target Alle IRF5 Proteine anzeigen
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-498
    Spezies
    • 13
    • 3
    • 1
    Human
    Quelle
    • 7
    • 5
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses IRF5 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Interferon Regulatory Factor 5/IRF5 (C-6His)
    Sequenz
    MNQSIPVAPT PPRRVRLKPW LVAQVNSCQY PGLQWVNGEK KLFCIPWRHA TRHGPSQDGD NTIFKAWAKE TGKYTEGVDE ADPAKWKANL RCALNKSRDF RLIYDGPRDM PPQPYKIYEV CSNGPAPTDS QPPEDYSFGA GEEEEEEEEL QRMLPSLSLT EDVKWPPTLQ PPTLRPPTLQ PPTLQPPVVL GPPAPDPSPL APPPGNPAGF RELLSEVLEP GPLPASLPPA GEQLLPDLLI SPHMLPLTDL EIKFQYRGRP PRALTISNPH GCRLFYSQLE ATQEQVELFG PISLEQVRFP SPEDIPSDKQ RFYTNQLLDV LDRGLILQLQ GQDLYAIRLC QCKVFWSGPC ASAHDSCPNP IQREVKTKLF SLEHFLNELI LFQKGQTNTP PPFEIFFCFG EEWPDRKPRE KKLITVQVVP VAARLLLEMF SGELSWSADS IRLQISNPDL KDRMVEQFKE LHHIWQSQQR LQPVAQAPPG AGLGVGQGPW PMHPAGMQLE HHHHHH
    Produktmerkmale
    Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.
    Reinheit
    >90% by SDS-PAGE
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 1 EU/ug
    Top Product
    Discover our top product IRF5 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 30% Glycerol, 1mM DTT, pH8.0
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Andere Bezeichnung
    IRF5 (IRF5 Produkte)
    Synonyme
    IRF5 Protein, irf5 Protein, SLEB10 Protein, AW491843 Protein, mirf5 Protein, im:7155364 Protein, zgc:76986 Protein, interferon regulatory factor 5 Protein, interferon regulatory factor 5 L homeolog Protein, IRF5 Protein, irf5 Protein, Irf5 Protein, irf5.L Protein
    Sub Type
    Fusionprotein
    Hintergrund
    Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.
    Alternative Names: Interferon Regulatory Factor 5, IRF-5, IRF5
    UniProt
    Q13568
    Pathways
    TLR Signalweg, Autophagie
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