TNFRSF4 Protein (AA 29-214) (Fc Tag)
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- Target Alle TNFRSF4 Proteine anzeigen
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 29-214
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Spezies
- Human, Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses TNFRSF4 Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Spezifität
- Binds to human and mouse OX40L.
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Human OX40 (aa 29-214) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF4 Protein
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Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 20-211) protein (His-Avi Tag)
TNFRSF4 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 20-211) protein (His-Avi Tag,Biotin)TNFRSF4 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) (Active) protein (Fc Tag)TNFRSF4 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) (Active) protein (His tag)TNFRSF4 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) protein (Fc Tag)TNFRSF4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) protein (His-Avi Tag)TNFRSF4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) protein (His-Avi Tag,Biotin)TNFRSF4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) (Active) protein (His tag)TNFRSF4 Spezies: Marmoset Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) (Active) protein (His tag,AVI tag,Biotin)TNFRSF4 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (Active) protein (His tag)TNFRSF4 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Blocks T cell proliferation induced by CD134L.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 50 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Andere Bezeichnung
- OX40 (TNFRSF4 Produkte)
- Synonyme
- TNFRSF4 Protein, ACT35 Protein, CD134 Protein, Ly-70 Protein, Ox40 Protein, TXGP1L Protein, Txgp1 Protein, OX40 Protein, TNF receptor superfamily member 4 Protein, tumor necrosis factor receptor superfamily, member 4 Protein, TNFRSF4 Protein, Tnfrsf4 Protein
- Hintergrund
- OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
- Molekulargewicht
- ~70kDa (SDS-PAGE)
- UniProt
- P43489
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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