TNFRSF4
(Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
Protein-Typ
Recombinant
Biologische Aktivität
Active
Proteineigenschaft
AA 29-216
Spezies
Human
Quelle
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses TNFRSF4 Protein ist gelabelt mit Fc Tag.
Sequenz
AA 29-216
Produktmerkmale
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.8 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
TNFRSF4
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
FACS
TNFRSF4
Spezies: Maus
Wirt: Human Cells
Recombinant
> 95 % as determined by SDS-PAGE
Active
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
PBS, pH 7.4
Handhabung
Please avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Upadhyaya, Lahdenranta, Hurov, Battula, Dods, Haines, Kleyman, Kristensson, Kublin, Lani, Ma, Mudd, Repash, Van Rietschoten, Stephen, You, Harrison, Chen, McDonnell, Brandish, Keen: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." in: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).
Target
TNFRSF4
(Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.