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IL1R1 Protein (AA 21-336) (Fc Tag)

IL1R1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
Produktnummer ABIN1344138
  • Target Alle IL1R1 Proteine anzeigen
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 21-336
    Spezies
    • 18
    • 10
    • 9
    Human
    Quelle
    • 14
    • 10
    • 4
    • 4
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL1R1 Protein ist gelabelt mit Fc Tag.
    Applikation
    SDS-PAGE (SDS)
    Spezifität
    Binds to human IL-1beta.
    Kreuzreaktivität
    Human
    Produktmerkmale
    Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
    Reinheit
    >95 % (SDS-PAGE)
    Endotoxin-Niveau
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product IL1R1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Blocks IL-1beta activity.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with 50 μL sterile water.
    Konzentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Target
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Abstract
    IL1R1 Produkte
    Synonyme
    CD121A Protein, D2S1473 Protein, IL-1R-alpha Protein, IL1R Protein, IL1RA Protein, P80 Protein, CD121a Protein, CD121b Protein, IL-iR Protein, Il1r-1 Protein, DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, interleukin 1 receptor type 1 Protein, interleukin 1 receptor, type I Protein, interleukin 1 receptor-like 1 Protein, IL1R1 Protein, Il1r1 Protein, Il1rl1 Protein
    Hintergrund
    IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
    Molekulargewicht
    ~80kDa (SDS-PAGE)
    UniProt
    P14778
    Pathways
    NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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