IL1R1 Protein (AA 21-336) (Fc Tag)
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- Target Alle IL1R1 Proteine anzeigen
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 21-336
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL1R1 Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Spezifität
- Binds to human IL-1beta.
- Kreuzreaktivität
- Human
- Produktmerkmale
- Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1R1 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Blocks IL-1beta activity.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 50 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Abstract
- IL1R1 Produkte
- Synonyme
- CD121A Protein, D2S1473 Protein, IL-1R-alpha Protein, IL1R Protein, IL1RA Protein, P80 Protein, CD121a Protein, CD121b Protein, IL-iR Protein, Il1r-1 Protein, DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, interleukin 1 receptor type 1 Protein, interleukin 1 receptor, type I Protein, interleukin 1 receptor-like 1 Protein, IL1R1 Protein, Il1r1 Protein, Il1rl1 Protein
- Hintergrund
- IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
- Molekulargewicht
- ~80kDa (SDS-PAGE)
- UniProt
- P14778
- Pathways
- NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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