CDK5 Protein (His tag)

Produktnummer ABIN1098713

Produktdetails

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CDK5 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Cyclin-dependent kinase 5, PSSALRE

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Andere Bezeichnung: CDK5 (CDK5 Produkte)

Synonyme: PSSALRE Protein, AW048668 Protein, Crk6 Protein, CDK5 Protein, CG8203 Protein, DmCdk5 Protein, Dmel\\CG8203 Protein, cdk5 Protein, zgc:101604 Protein, cyclin dependent kinase 5 Protein, cyclin-dependent kinase 5 Protein, Cyclin-dependent kinase 5 Protein, cyclin-dependent kinase 5 L homeolog Protein, Cyclin-dependent-like kinase 5 Protein, CDK5 Protein, Cdk5 Protein, cdk5 Protein, cdk5.L Protein, cdk-5 Protein

Hintergrund: CDK5, also known as cell division protein kinase 5, is a member of the cyclin-dependent kinase family. It is required for proper development of the brain and to be activated, CDK5 must associate with CDK5R1 or CDK5R2. Unlike other cyclin dependent kinases, it does not also require phosphorylation on the T loop so that binding with the activator is sufficient to activate the kinase. This protein is involved in the processes of neuronal maturation and migration, phosphorylating the key intracellular adaptor of the reelin signaling chain. Recombinant human CDK5 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 35.8 kDa(316aa)

NCBI Accession: NP_004926

Pathways: Zellzyklus, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis