PRKAB2 Protein (His tag)
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- Target Alle PRKAB2 Proteine anzeigen
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PRKAB2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PRKAB2 Protein
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Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) protein (His-IF2DI Tag)
PRKAB2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) protein (GST tag)PRKAB2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-110) protein (GST tag)PRKAB2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) protein (Strep Tag)Crystallography grade PRKAB2 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-271) protein (Strep Tag)Crystallography grade PRKAB2 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Kommentare
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Synonyms: 5'-AMP-activated protein kinase subunit beta-2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2 M Urea
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- Andere Bezeichnung
- PRKAB2 (PRKAB2 Produkte)
- Synonyme
- prkab2 Protein, MGC64365 Protein, PRKAB2 Protein, DKFZp469M1118 Protein, 5730553K21Rik Protein, AW049591 Protein, BB124140 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog Protein, protein kinase AMP-activated non-catalytic subunit beta 2 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit Protein, prkab2.L Protein, PRKAB2 Protein, prkab2 Protein, Prkab2 Protein
- Hintergrund
- PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Recombinant human PRKAB2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 32.8 kDa(296aa)
- NCBI Accession
- NP_005390
- Pathways
- AMPK Signaling, Warburg Effekt
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