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PRKAB2 Produkte

(Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))

Kategorien

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeq, Jul 2008].

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Ausgewählte PRKAB2 Kategorien

PRKAB2 Antikörper

High quality antibodies with extensive validation data.

PRKAB2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PRKAB2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, FACS, ICC
Validierungen
  • (7)
Kat. Nr. ABIN5611226
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7262869
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, FACS, ICC, Neut
Validierungen
  • (4)
Kat. Nr. ABIN5611225
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene PRKAB2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124660
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316215
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316217
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PRKAB2 Produkten

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Minokoshi, Alquier, Furukawa, Kim, Lee, Xue, Mu, Foufelle, Ferré, Birnbaum, Stuck, Kahn: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." in: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).

Park, Paulsen, Gammon, Mustard, Hardie, Winder: "Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 93, Issue 6, pp. 2081-8, (2002) (PubMed).

Prochazka, Farook, Ossowski, Wolford, Bogardus: "Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians." in: Molecular and cellular probes, Vol. 16, Issue 6, pp. 421-7, (2002) (PubMed).

Synonyme und alternative Namen zu PRKAB2

protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog (prkab2.L), protein kinase AMP-activated non-catalytic subunit beta 2 (PRKAB2), protein kinase, AMP-activated, beta 2 non-catalytic subunit (PRKAB2), protein kinase, AMP-activated, beta 2 non-catalytic subunit (prkab2), protein kinase, AMP-activated, beta 2 non-catalytic subunit (Prkab2), protein kinase AMP-activated non-catalytic subunit beta 2 (Prkab2), 5730553K21Rik, AW049591, BB124140, DKFZp469M1118, MGC64365, prkab2, PRKAB2

Bezeichner auf Proteinebene für PRKAB2

  • protein kinase, AMP-activated, beta 2 non-catalytic subunit
  • AMP-activated protein kinase beta 2 non-catalytic subunit
  • 5'-AMP-activated protein kinase subunit beta-2
  • 5'-AMP-activated protein kinase, beta-2 subunit
  • AMPK beta 2
  • AMPK beta-2 chain
  • AMPK subunit beta-2
  • AMP-activated protein kinase beta-2 regulatory subunit
  • AMPK beta-2
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