PRKG1 Produkte
(Protein Kinase, CGMP-Dependent, Type I (PRKG1))
Kategorien
Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity. [provided by RefSeq, Sep 2011].
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Ausgewählte PRKG1 Kategorien
PRKG1 Antikörper
High quality antibodies with extensive validation data.
PRKG1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PRKG1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PRKG1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN392536
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN562400
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN562402
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PRKG1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969729
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958936
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958937
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PRKG1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570613
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316295
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316297
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PRKG1 Produkten
: "A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16557-66, (2013) (PubMed).Synonyme und alternative Namen zu PRKG1
protein kinase, cGMP-dependent, type Ia (prkg1a), protein kinase, cGMP-dependent, type I (PRKG1), protein kinase, cGMP-dependent, type I (prkg1), protein kinase, cGMP-dependent, type 1 (Prkg1), protein kinase, cGMP-dependent, type I (Prkg1), 1, AW125416, cGK, cGk1, cGK 1, cGK1, cGKI, CGKI, cGKI-alpha, cGKI-BETA, cGKI-beta, Gm19690, PKG, Pkgi, prkg1, PRKG1B, Prkg1b, Prkg1beta, PRKGR1B, Prkgr1b, zgc:63955Bezeichner auf Proteinebene für PRKG1
- cGMP-dependent protein kinase 1
- protein kinase, cGMP-dependent, type I
- cGMP-dependent protein kinase 1, beta isozyme
- cGMP-dependent protein kinase I alpha
- cGK I alpha
- cGMP-dependent protein kinase 1-like
- cGMP dependent protein kinase type 1
- protein kinase, cGMP-dependent, regulatory, type I, beta
- CGK 1 alpha
- cGK 1 beta
- cGK1
- cGKI-alpha
- cGMP-dependent protein kinase 1, alpha isozyme
- cGMP-dependent protein kinase I
- cGK 1
- PKG1 alpha
- cGMP-dependent protein kinase type 1 alpha
- cGMP-dependent protein kinase type I beta
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