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PRKAA1/PRKAA2 Produkte

(AMPK1/AMPK2)

Kategorien

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].

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Empfohlene PRKAA1/PRKAA2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Monkey, Mouse, Rat
Applikation WB, ELISA, IHC (p), IF
Validierungen
  • (3)
Kat. Nr. ABIN7250794
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Pig, Rat, Sheep
Applikation WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro)
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN752368
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF
Validierungen
  • (1)
Kat. Nr. ABIN1842476
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PRKAA1/PRKAA2 Produkten

Saito, Chikenji, Ozasa, Fujimiya, Yamashita, Gingery, Iba: "PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome." in: Scientific reports, Vol. 7, Issue 1, pp. 16192, (2019) (PubMed).

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Wang, Zhao, Yu, Feng, Zhang, Kou, Chu, Cui, Li, Zhang, Shen, Min: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." in: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).

Zhao, Zhang, Liu, Zhang, Hao, Li, Chen, Shen, Tang, Min, Meng, Wang, Yi, Zhang: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." in: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).

Arduini, Serviddio, Escobar, Tormos, Bellanti, Viña, Monsalve, Sastre: "Mitochondrial biogenesis fails in secondary biliary cirrhosis in rats leading to mitochondrial DNA depletion and deletions." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 301, Issue 1, pp. G119-27, (2011) (PubMed).

Kim, Tannenbaum, White: "Global phosphoproteome of HT-29 human colon adenocarcinoma cells." in: Journal of proteome research, Vol. 4, Issue 4, pp. 1339-46, (2005) (PubMed).

Woods, Vertommen, Neumann, Turk, Bayliss, Schlattner, Wallimann, Carling, Rider: "Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis." in: The Journal of biological chemistry, Vol. 278, Issue 31, pp. 28434-42, (2003) (PubMed).

Synonyme und alternative Namen zu PRKAA1/PRKAA2

protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2), protein kinase AMP-activated catalytic subunit alpha 2 (Prkaa2), protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2), 2310008I11Rik, A830082D05, AMPK, Ampk, AMPK2, AMPKa2, Ampka2, AMPKalpha2, PRKAA

Bezeichner auf Proteinebene für PRKAA1/PRKAA2

  • 5'-AMP-activated protein kinase catalytic subunit alpha-2
  • 5'-AMP-activated protein kinase, catalytic alpha-2 chain
  • ACACA kinase
  • AMPK subunit alpha-2
  • AMPK-alpha-2 chain
  • HMGCR kinase
  • acetyl-CoA carboxylase kinase
  • hydroxymethylglutaryl-CoA reductase kinase
  • AMP-activated protein kinase
  • AMPK alpha-2 chain
  • AMP-activated protein kinase alpha-2 variant B
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