SMAD2 Protein (AA 2-467, full length) (His tag)
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- Target Alle SMAD2 Proteine anzeigen
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 2-467, full length
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses SMAD2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS), ELISA
- Sequenz
- SSILPFTPPV VKRLLGWKKS AGGSGGAGGG EQNGQEEKWC EKAVKSLVKK LKKTGRLDEL EKAITTQNCN TKCVTIPSTC SEIWGLSTPN TIDQWDTTGL YSFSEQTRSL DGRLQVSHRK GLPHVIYCRL WRWPDLHSHH ELKAIENCEY AFNLKKDEVC VNPYHYQRVE TPVLPPVLVP RHTEILTELP PLDDYTHSIP ENTNFPAGIE PQSNYIPETP PPGYISEDGE TSDQQLNQSM DTGSPAELSP TTLSPVNHSL DLQPVTYSEP AFWCSIAYYE LNQRVGETFH ASQPSLTVDG FTDPSNSERF CLGLLSNVNR NATVEMTRRH IGRGVRLYYI GGEVFAECLS DSAIFVQSPN CNQRYGWHPA TVCKIPPGCN LKIFNNQEFA ALLAQSVNQG FEAVYQLTRM CTIRMSFVKG WGAEYRRQTV TSTPCWIELH LNGPLQWLDK VLTQMGSPSV RCSSMS
- Produktmerkmale
- Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
- Reinheit
- 90 %
- Top Product
- Discover our top product SMAD2 Protein
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SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) protein (GST tag)
SMAD2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) protein (His tag)SMAD2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 1-467) protein (His tag)SMAD2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS
SMAD, Mothers Against DPP Homolog 2 (SMAD2) protein (GST tag,His tag)SMAD2 Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) protein (His tag)Crystallography grade SMAD2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) protein (His tag)Crystallography grade SMAD2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SMAD2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Kommentare
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0, 200 mM Imidazole
- Lagerung
- -20 °C
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- Target
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- Andere Bezeichnung
- Mothers against decapentaplegic homolog 2 (SMAD2 Produkte)
- Synonyme
- JV18 Protein, JV18-1 Protein, MADH2 Protein, MADR2 Protein, hMAD-2 Protein, hSMAD2 Protein, jv18 Protein, Xmad2 Protein, madh2 Protein, madr2 Protein, XSmad2 Protein, hmad-2 Protein, hsmad2 Protein, jv18-1 Protein, smad-2 Protein, fj43c06 Protein, wu:fj43c06 Protein, 7120426M23Rik Protein, Madh2 Protein, Madr2 Protein, Smad-2 Protein, mMad2 Protein, MAD homolog 2 Protein, Mothers against DPP homolog 2 Protein, SMAD 2 Protein, Smad2 Protein, SMAD family member 2 Protein, SMAD family member 2-Z Protein, SMAD family member 2 S homeolog Protein, SMAD2 Protein, SMAD2Z Protein, smad2 Protein, smad2.S Protein, Smad2 Protein
- Hintergrund
- Synonyms: JV18-1,Mad-related protein 2
- Molekulargewicht
- 56.2 kD
- UniProt
- Q15796
- Pathways
- Zellzyklus, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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