Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Produkte
(Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
Kategorien
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].
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Ausgewählte Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Kategorien
Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Antikörper
High quality antibodies with extensive validation data.
Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN6145638
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p), IF
Validierungen
- (6)
Kat. Nr.
ABIN1500202
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Mouse
Applikation
WB, IHC, IHC (p), IF
Validierungen
- (7)
Kat. Nr.
ABIN1500203
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3094659
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3137255
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2728968
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Produkten
: "The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma." in: Molecular cancer, Vol. 17, Issue 1, pp. 93, (2018) (PubMed).: "Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLC? and to Activate p44/42 MAPK in Human Aortic Endothelial ..." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132835, (2015) (PubMed).
: "Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin ..." in: Endocrinology, Vol. 145, Issue 6, pp. 2845-57, (2004) (PubMed).
: "The IL-1 receptor accessory protein is essential for PI 3-kinase recruitment and activation." in: Biochemical and biophysical research communications, Vol. 316, Issue 4, pp. 1022-8, (2004) (PubMed).
: "Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells." in: Oncogene, Vol. 22, Issue 3, pp. 392-400, (2003) (PubMed).
: "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." in: Journal of virology, Vol. 77, Issue 4, pp. 2539-49, (2003) (PubMed).
: "Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation." in: Molecular pharmacology, Vol. 63, Issue 3, pp. 639-45, (2003) (PubMed).
: "Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45." in: Journal of cancer research and clinical oncology, Vol. 130, Issue 1, pp. 8-14, (2003) (PubMed).
Synonyme und alternative Namen zu Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG), phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (Pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (Pik3cg), si:rp71-17i16.5 (si:rp71-17i16.5), 5830428L06Rik, p110gamma, p120-PI3K, PI3CG, PI3K, Pi3k, pi3k, PI3Kgamma, PIK3, wu:fb15d07, zgc:77033Bezeichner auf Proteinebene für Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide
- 1-phosphatidylinositol 3-kinase
- PI3-kinase subunit gamma
- PI3K-gamma
- p110-gamma
- p110gamma
- p120-PI3K
- phosphatidylinositol 3 kinase gamma, p110 gamma
- phosphatidylinositol 3-kinase catalytic 110-kD gamma
- phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
- phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
- phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- phosphoinositide-3-kinase gamma catalytic subunit
- phosphoinositide-3-kinase, catalytic, gamma polypeptide
- ptdIns-3-kinase subunit gamma
- ptdIns-3-kinase subunit p110-gamma
- serine/threonine protein kinase PIK3CG
- phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like
- PI3Kgamma
- catalytic subunit of G-beta-gamma-activated
- phosphoinositide-3-kinase catalytic gamma polypeptide
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