Phospholamban Produkte
(Phospholamban (PLN))
Kategorien
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].
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Ausgewählte Phospholamban Kategorien
Phospholamban Antikörper
High quality antibodies with extensive validation data.
Phospholamban ELISA Kits
Reliable ELISA kits for a wide range of species.
Phospholamban Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Phospholamban Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7442687
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC, FACS
Validierungen
- (5)
Kat. Nr.
ABIN3032226
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validierungen
- (2)
Kat. Nr.
ABIN682468
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Phospholamban ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969290
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958555
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1571936
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Phospholamban Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315443
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3120679
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3097101
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Phospholamban Produkten
: "Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic and "Reopening"." in: PloS one, Vol. 16, Issue 4, pp. e0250319, (2021) (PubMed).: "Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes." in: Cellular signalling, Vol. 63, pp. 109362, (2019) (PubMed).
: "Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure." in: Circulation, Vol. 138, Issue 11, pp. 1144-1154, (2019) (PubMed).
: "Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation." in: Cellular signalling, Vol. 27, Issue 9, pp. 1807-15, (2015) (PubMed).
: "Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction." in: Molecular and cellular biology, Vol. 32, Issue 4, pp. 740-50, (2012) (PubMed).
: "The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathy." in: European journal of heart failure, Vol. 11, Issue 11, pp. 1031-5, (2009) (PubMed).
: "Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes." in: American journal of physiology. Cell physiology, Vol. 296, Issue 5, pp. C992-C1002, (2009) (PubMed).
: "Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 32, Issue 2, pp. 333-9, (2007) (PubMed).
: "Phospholamban: a key determinant of cardiac function and dysfunction." in: Archives des maladies du coeur et des vaisseaux, Vol. 98, Issue 12, pp. 1239-43, (2006) (PubMed).
: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).
Synonyme und alternative Namen zu Phospholamban
phospholamban (PLN), phospholamban (pln), phospholamban (Pln), cmd1p, CMD1P, CMH18, LOC100226261, plb, PLB, Plb, PlmBezeichner auf Proteinebene für Phospholamban
- phospholamban
- cardiac phospholamban
- PLB
Haben Sie etwas anderes gesucht?
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- phosphoglycerate Mutase 1 (Brain)
- Phosphoglycerate Mutase
- Phosphoglycerate Kinase
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- Phosphoglucomutase 3
- Phosphoglucomutase 2
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- Phosphodiesterase I
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- PHOSPHO2
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- Phospho-Extracellular Signal-Regulated Kinase
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- Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta
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- Phospholipase
- Phospholipase B
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- Phospholipase C beta 2
- Phospholipase C beta 4
- Phospholipase C delta 3
- Phospholipase C gamma 1
- Phospholipase C gamma 2
- Phospholipase D
- Phospholipase D2
- Phospholipase D4
- Phospholipid-binding Lipoprotein mlaA
- phosphoribosyl Pyrophosphate Synthetase 1
- Phosphorylase A
- Phosphorylase B
- Phosphorylase, Glycogen, Muscle
- Phosphoserine
- Phosphothreonine
- Phosphotransacetylase
- Phosphotyrosine
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