Pyruvate Kinase, Liver and RBC (PKLR) (N-Term) Peptid
PKLR
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle PKLR Produkte
- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- TVDPAFRTRG NANTVWVDYP NIVRVVPVGG RIYIDDGLIS LVVQKIGPEG
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PKLR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
- Synonyme
- PK1 Peptide, PKL Peptide, PKR Peptide, PKRL Peptide, RPK Peptide, Pklg Peptide, wu:fd15e01 Peptide, wu:fi37e08 Peptide, pk1 Peptide, PKLR Peptide, Pk-1 Peptide, Pk1 Peptide, R-PK Peptide, pklr Peptide, pyruvate kinase L/R Peptide, pyruvate kinase, liver and RBC Peptide, pyruvate kinase, liver and RBC L homeolog Peptide, pyruvate kinase liver and red blood cell Peptide, pyruvate kinase PKLR-like Peptide, PKLR Peptide, Pklr Peptide, pklr Peptide, pklr.L Peptide, LOC100621940 Peptide
- Hintergrund
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The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PKLR,PK1,PKL,
Protein Size: 574 - Gen-ID
- 5313
- UniProt
- P30613
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