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Pyruvate Kinase, Liver and RBC (PKLR) Peptid

PKLR Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN981814
  • Target Alle PKLR Produkte
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PKLR antibody (Catalog #: ARP41699_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    Synonyme
    PK1 Peptide, PKL Peptide, PKR Peptide, PKRL Peptide, RPK Peptide, Pklg Peptide, wu:fd15e01 Peptide, wu:fi37e08 Peptide, pk1 Peptide, PKLR Peptide, Pk-1 Peptide, Pk1 Peptide, R-PK Peptide, pklr Peptide, pyruvate kinase L/R Peptide, pyruvate kinase, liver and RBC Peptide, pyruvate kinase, liver and RBC L homeolog Peptide, pyruvate kinase liver and red blood cell Peptide, pyruvate kinase PKLR-like Peptide, PKLR Peptide, Pklr Peptide, pklr Peptide, pklr.L Peptide, LOC100621940 Peptide
    Hintergrund
    PKLR is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Alternatively spliced transcript variants encoding distinct isoforms have been described.

    Alias Symbols: PK1, PKL, RPK, PKR, PKRL

    Protein Interaction Partner: MYOC,ARHGEF6,KIF23,OTUD5,PAK1,PXN,USP3,USPL1

    Protein Size: 543
    Molekulargewicht
    58 kDa
    Gen-ID
    5313
    NCBI Accession
    NM_181871, NP_870986
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