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PKLR Produkte

(Pyruvate Kinase, Liver and RBC (PKLR))

Kategorien

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte PKLR Kategorien

PKLR Antikörper

High quality antibodies with extensive validation data.

PKLR ELISA Kits

Reliable ELISA kits for a wide range of species.

PKLR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PKLR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7431302
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7431305
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (4)
Kat. Nr. ABIN950030
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PKLR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6959012
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959013
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959014
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PKLR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315223
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315225
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124725
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PKLR Produkten

Ahmad-Molaei, Pourhamzeh, Ahadi, Khodagholi, Hassanian-Moghaddam, Haghparast: "Time-Dependent Changes in the Serum Levels of Neurobiochemical Factors After Acute Methadone Overdose in Adolescent Male Rat." in: Cellular and molecular neurobiology, (2020) (PubMed).

Kim, Gu, Yoo, Han, Kim, Nam-Goong, Kim, Kim: "Contact system activation and high thrombin generation in hyperthyroidism." in: European journal of endocrinology, Vol. 176, Issue 5, pp. 583-589, (2017) (PubMed).

Ren, Yang, Wang, Ma: "The effects of PGC-1α on the proliferation and energy metabolism of malignant endometrial cancer cells." in: OncoTargets and therapy, Vol. 8, pp. 769-74, (2015) (PubMed).

Kowalski, Nocon, Gamian, Kołodziej, Rakus: "Association of C-terminal region of phosphoglycerate mutase with glycolytic complex regulates energy production in cancer cells." in: Journal of cellular physiology, Vol. 227, Issue 6, pp. 2613-21, (2012) (PubMed).

Jindal, Merchant, Balschi, Zhangand, Koren: "Proteomic analyses of transgenic LQT1 and LQT2 rabbit hearts elucidate an increase in expression and activity of energy producing enzymes." in: Journal of proteomics, Vol. 75, Issue 17, pp. 5254-65, (2012) (PubMed).

Yang, Nath, Opperman, Chan: "The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells." in: Molecular biology of the cell, Vol. 21, Issue 19, pp. 3449-58, (2010) (PubMed).

Wang, Chu, Das, Ren, Hasstedt, Elbein: "Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians." in: Diabetes, Vol. 51, Issue 9, pp. 2861-5, (2002) (PubMed).

Valentini, Chiarelli, Fortin, Dolzan, Galizzi, Abraham, Wang, Bianchi, Zanella, Mattevi: "Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23807-14, (2002) (PubMed).

Mateu, Pérez-Lezaun, Martínez-Arias, Andrés, Vallés, Bertranpetit, Calafell: "PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations." in: Human genetics, Vol. 110, Issue 6, pp. 532-44, (2002) (PubMed).

Synonyme und alternative Namen zu PKLR

pyruvate kinase L/R (PKLR), pyruvate kinase, liver and RBC (Pklr), pyruvate kinase L/R (pklr), pyruvate kinase, liver and RBC L homeolog (pklr.L), pyruvate kinase, liver and RBC (pklr), pyruvate kinase, liver and RBC (PKLR), pyruvate kinase liver and red blood cell (Pklr), pyruvate kinase L/R (Pklr), pyruvate kinase PKLR-like (LOC100621940), Pk-1, PK1, pk1, Pk1, PKL, Pklg, PKLR, pklr, PKR, PKRL, R-PK, RPK, wu:fd15e01, wu:fi37e08

Bezeichner auf Proteinebene für PKLR

  • R-type/L-type pyruvate kinase
  • pyruvate kinase 1
  • pyruvate kinase PKLR
  • pyruvate kinase isozyme R/L
  • pyruvate kinase isozymes L/R
  • pyruvate kinase isozymes R/L
  • pyruvate kinase type L
  • pyruvate kinase, liver and blood cell
  • red cell/liver pyruvate kinase
  • L-PK
  • pyruvate kinase, liver and red blood cell
  • pyruvate kinase, liver and RBC
  • Pyruvate kinase isozyme R
  • Pyruvate kinase isozymes R/L
  • pyruvate kinase isozymes R/L-like
  • secretory carrier-associated membrane protein 3-like
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