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PKD2 Produkte

(Protein Kinase D2 (PKD2))

Kategorien

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte PKD2 Kategorien

PKD2 Antikörper

High quality antibodies with extensive validation data.

PKD2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PKD2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PKD2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p), IF, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN2855325
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN565195
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Dog, Human, Monkey, Rat
Applikation WB, IF, FACS
Validierungen
  • (4)
Kat. Nr. ABIN1500413
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PKD2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1116796
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1116794
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1116795
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PKD2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316288
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316286
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Baculovirus infected Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN7317066
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PKD2 Produkten

Zheng, Qian, Varghese, Baker, Fuchs: "Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2." in: Molecular and cellular biology, Vol. 31, Issue 4, pp. 710-20, (2011) (PubMed).

Azoitei, Kleger, Schoo, Thal, Brunner, Pusapati, Filatova, Genze, Möller, Acker, Kuefer, Van Lint, Baust, Adler, Seufferlein: "Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation." in: Neuro-oncology, Vol. 13, Issue 7, pp. 710-24, (2011) (PubMed).

Zheng, Qian, Baker, Fuchs: "Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35733-41, (2011) (PubMed).

Pusapati, Krndija, Armacki, von Wichert, von Blume, Malhotra, Adler, Seufferlein: "Role of the second cysteine-rich domain and Pro275 in protein kinase D2 interaction with ADP-ribosylation factor 1, trans-Golgi network recruitment, and protein transport." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1011-22, (2010) (PubMed).

Liu, Evans, Britton, Zachary: "The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis." in: Oncogene, Vol. 27, Issue 21, pp. 2989-98, (2008) (PubMed).

Sharlow, Giridhar, LaValle, Chen, Leimgruber, Barrett, Bravo-Altamirano, Wipf, Lazo, Wang: "Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33516-26, (2008) (PubMed).

Yuan, Lugea, Zheng, Gukovsky, Edderkaoui, Rozengurt, Pandol: "Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 295, Issue 6, pp. G1190-201, (2008) (PubMed).

Bossard, Bresson, Polishchuk, Malhotra: "Dimeric PKD regulates membrane fission to form transport carriers at the TGN." in: The Journal of cell biology, Vol. 179, Issue 6, pp. 1123-31, (2007) (PubMed).

Yeaman, Ayala, Wright, Bard, Bossard, Ang, Maeda, Seufferlein, Mellman, Nelson, Malhotra: "Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network." in: Nature cell biology, Vol. 6, Issue 2, pp. 106-12, (2004) (PubMed).

Rey, Yuan, Rozengurt: "Intracellular redistribution of protein kinase D2 in response to G-protein-coupled receptor agonists." in: Biochemical and biophysical research communications, Vol. 302, Issue 4, pp. 817-24, (2003) (PubMed).

Synonyme und alternative Namen zu PKD2

protein kinase D2 (PRKD2), protein kinase D2 (Prkd2), serine/threonine-protein kinase D2 (LOC100407181), AI325941, nPKC-D2, PKD2, PRKD2, RGD1308054

Bezeichner auf Proteinebene für PKD2

  • serine/threonine-protein kinase D2
  • nPKC-D2
  • protein kinase D2
  • serine/threonine-protein kinase D2-like
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