PKD2 Protein (His-GST)
Kurzübersicht für PKD2 Protein (His-GST) (ABIN7317066)
Target
Alle PKD2 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses PKD2 Protein ist gelabelt mit His-GST.
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Verwendungszweck
- Recombinant Human PRKD2/PKD2 Protein (His & GST Tag)
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Sequenz
- Met 1-Leu 878
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Produktmerkmale
- A DNA sequence encoding the amino acid sequence (Met 1-Leu 878) of human PRKD2 (NP_057541.2) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be > 30 nmol/min/mg using synthetic CREBtide peptide (KRREILSRRPSYR) as substrate.
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Protein Kinase D2 (PKD2) (AA 1-878) protein (GST tag)
PKD2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase D2 (PKD2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PKD2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Kinase D2 (PKD2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PKD2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied as sterile solution of 50 mM Tris, 500 mM NaCl, 0.5 mM PMSF, 10 % glycerol, pH 8.0
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Konservierungsmittel
- PMSF
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- PKD2 (Protein Kinase D2 (PKD2))
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Andere Bezeichnung
- PRKD2/PKD2
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Hintergrund
- HSPC187,PKD2,nPKC-D2,Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is widely expressed. It contains onePH domain, twophorbol-ester/DAG-type zinc fingers and oneprotein kinase domain. PRKD2 / PKD2 is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains bind DAG, mediating translocation to membranes. Autophosphorylation of Ser-710 and phosphorylation of Ser-706 by PKC relieves auto-inhibition by the PH domain. PRKD2 / PKD2 converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
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Molekulargewicht
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Calculated MW: 124 kDa
Observed MW: 120 kDa
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Gen-ID
- 25865
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NCBI Accession
- NP_057541
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UniProt
- Q9BZL6
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Pathways
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
Target
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