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Human Prostate Specific Antigen Protein expressed in Human - ABIN934764
Harris, Lenz, Hankey, MacVittie, Farese, Nakajima, Hasumi, Mann: Products of anti-CD3/anti-CD28 activated lymphocytes induce differentiation and maturation of dendritic cells and have adjuvant-like activity in vitro and in vivo. in Clinical immunology (Orlando, Fla.) 2008
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Human Prostate Specific Antigen Protein expressed in Human - ABIN934765
Marshall, Rudnick, McCarthy, Mateo, Harris, McCauley, Snyder: Interleukin-18 enhances Th1 immunity and tumor protection of a DNA vaccine. in Vaccine 2005
Show all 2 Pubmed References
Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.
Men with mild to no lower urinary tract symptoms (LUTS) but increased baseline PSA are at increased risk of developing incident LUTS presumed due to benign prostatic hyperplasia
PSA-density might inform biopsy decisions, and spare some men from the morbidity associated with a prostate biopsy and diagnosis of low-grade prostate cancer.
PSA was the only independent predictor of extensive lymph node invasion and could be an important preoperative factor for stratifying high-risk patients.
ue to the biocompatibility, multivalency, stability, and high structural homogeneity, the t-PSA-specific landscape phage demonstrates as a novel specific interface in biosensors.
Based on the target-induced catalytic hairpin assembly and bimetallic catalyst, the enzyme-free recycling amplification strategy for sensitive detection of prostate specific antigen (PSA) has been designed
The prepared biosensor can assay from 0 to 500ng/mL of prostate specific antigen (PSA) level within 2h with the detection limit of 1.18ng/mL by the measurement of resistance change. The resistance change was caused by site selective interaction between PSA and PSA-antigen with an inexpensive bench top digital multimeter (5 1/2 digits)
he superwettable f-PSA microchip can accurately detect human serum samples with excellent correlations with chemiluminescence immunoassay in the clinic, demonstrating its great potential as a sensitive and reliable sensing platform for biological analysis and clinical diagnosis.
The 12-week PSA (zeige PLAG1 Proteine) response rate was 88% (22/25) and 22% (4/18), median time to PSA (zeige PLAG1 Proteine) progression was 18.2 months [95% confidence interval (CI), 8.3 months-not reached) and 3.7 months (95% CI, 2.8-5.6 months), and median time on treatment 21 months (range, 2.6-37.5) and 4.9 months (range, 1.3-23.2), for the AAP (zeige APEH Proteine)-naive and post-AAP (zeige APEH Proteine) cohorts, respectively.
The results support that u-PSA provides useful information for predicting predicting biochemical recurrence after radical prostatectomy . This can be beneficial to avoid unnecessary adjuvant treatments or to start them earlier for selected patients
Nucleocytoplasmic transfer of cyclin dependent kinase 5 (zeige CDK5 Proteine) and its binding to puromycin-sensitive aminopeptidase (zeige NPEPPS Proteine) in Dictyostelium discoideum
findings show that by promoting autophagic protein clearance, PSA helps protect against accumulation of aggregation-prone proteins and proteotoxicity
These data indicate that PSA (zeige NPEPPS Proteine) may play a role in limiting MHC class I Ag presentation in dendritic cells in vivo but that it is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags (zeige GLA Proteine).
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
, prostate specific antigen
, prostate-specific antigen
, kallikrein-related peptidase 3
, S1 kallikrein
, glandular kallikrein-3, submandibular
, kallikrein 1-related peptidase c10-like 2
, kallikrein 3
, submaxillary gland S1 kallikrein
, tissue kallikrein
, cytosol alanyl aminopeptidase
, puromycin-sensitive aminopeptidase