anti-Human STAT2 Antikörper für Immunocytochemistry

Recommended STAT2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) Antikörper
  • wu:fj84d07
  • p113
  • stat2
  • 1600010G07Rik
  • AW496480
  • ISGF-3
  • P113
  • STAT113
  • signal transducer and activator of transcription 2
  • AGAP000099-PA
  • stat2
  • STAT2
  • Stat2
Epitop
pTyr690
45
35
18
17
15
15
13
11
11
9
8
7
7
7
6
5
5
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
258
99
81
10
3
3
2
2
2
2
1
Wirt
Kaninchen
279
19
1
Klonalität
Polyklonal
Konjugat
Dieser STAT2 Antikörper ist unkonjugiert
12
10
9
6
6
6
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
243
116
108
46
27
23
17
12
8
6
3
3
3
2
1
1
1
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN6256788
$ 390.77
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
13 ABIN6265314 ELISA ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
13 ABIN1860648 ICC IHC WB Rabbit IgG AA 616-849 Anmelden zum Anzeigen Polyclonal 0
7 ABIN6271420 ELISA ICC IF WB Rabbit IgG pTyr631 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) Antikörper
Epitop pTyr690
(45), (35), (18), (17), (15), (15), (13), (11), (11), (9), (8), (7), (7), (7), (6), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Ratte (Rattus)
(258), (99), (81), (10), (3), (3), (2), (2), (2), (2), (1)
Wirt Kaninchen
(279), (19), (1)
Klonalität
Polyklonal
Konjugat Dieser STAT2 Antikörper ist unkonjugiert
(12), (10), (9), (6), (6), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Applikation ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(243), (116), (108), (46), (27), (23), (17), (12), (8), (6), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-STAT2 Antikörper

Target Details STAT2 Anwendungsinformationen Handhabung Bilder
Spezifität Phospho-STAT2 (Tyr690) Antibody detects endogenous levels of STAT2 only when phosphorylated at Tyrosine 690
Kreuzreaktivität Human, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human STAT2 around the phosphorylation site of Tyrosine 690
Isotyp IgG
Plasmids, Primers & others

Target Details STAT2

Produktdetails anti-STAT2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung STAT2 (STAT2 Antibody Abstract)
Hintergrund

Description: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state (PubMed:9020188, PubMed:23391734). Acts as a regulator of mitochondrial fission by modulating the phosphorylation of DNM1L at 'Ser-616' and 'Ser-637' which activate and inactivate the GTPase activity of DNM1L respectively (PubMed:26122121).

Gene: STAT2

Molekulargewicht 113kDa
Gen-ID 6773
UniProt P52630
Pathways JAK-STAT Signalweg, Hepatitis C, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-STAT2 Antikörper Target Details STAT2 Handhabung Bilder zurück nach oben
Applikations-hinweise WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-STAT2 Antikörper Target Details STAT2 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months

Bilder

Produktdetails anti-STAT2 Antikörper Target Details STAT2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (pTyr690) antibody (ABIN6256788) ABIN6267551 at 1/100 staining human Breast carcinoma tissue sections by IHC-P. The ti...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (pTyr690) antibody (ABIN6256788) ABIN6267551 staining HeLa by IF/ICC. The sample were fixed with PFA and permeabilized...
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (pTyr690) antibody (ABIN6256788) Western blot analysis of STAT2 phosphorylation expression in IFN treated HeLa whole c...
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (pTyr690) antibody (ABIN6256788) Western blot analysis of Phospho-STAT2 (Tyr690) expression in various lysates